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All Posts Tagged: stem cells

Aesthetic Trends Utilizing Stem Cell Science

The Role of Stem Cells and Stem Cell Derivatives in Aesthetics

The United States is currently spending nearly $1 billion a year on stem cell research, indicating an understanding of the life-changing potential stem cells have in the fields of medicine, aesthetics and beyond.

In 2013 Dr. Norma Kassardjian stated “Research at the Mayo Clinic has shown stem cell therapy to delay or even eliminate joint replacement procedures, a revelation discovered through the stem cells’ ability to repair damaged cartilage in the hips and knees. With all of these promising results, it is becoming clearer and clearer that we are on our way to a medical revolution, and it is stem cell research that is leading the charge.”

And recently, the National Institutes of Health (NIH) commented that overall, clinical advances using various stem cells suggest a promising future for opening a new cell therapeutic strategy in plastic surgery. Let’s take a look at what this new future holds now.

Stem Cell Face Lift

The stem cell facelift is a complete non-surgical facial rejuvenation procedure that has been performed at the Plastic Surgery Center Internationale for over four years with outstanding results. The main function of the procedure is to restore both the youthful contour and shape of the face as well as improve skin quality, tightness and color irregularities caused by the aging process, sun exposure and other environmental damage. Patients who have undergone this procedure frequently avoid or markedly reduce the need for other maintenance procedures like Botox and cosmetic filler injections. The function of the procedure is based on the regenerative capacity of a group of cells called adult stem cells.

What makes the stem cell facelifts unique and different from other fat transplant procedures is the fact that the abdominal fat and stem cells are mixed with a specific combination of growth factors that help both the stem cells and adipose tissues grow into the needed tissue to restore both the fat to enhance the volume of the face as well as skin elements to improve both the quality and texture of the skin.

Stem Cells in Cosmetic Surgery

Regenerative cell-based strategies, such as those encompassing the use of stem cells, hold tremendous promise for augmentation of the soft tissue space. Adult stem cells such as mesenchymal stem cells (MSCs) circumvent many of the ethical and technical issues associated with embryonic stem cells (ESCs) as they can be isolated from developed tissues including bone marrow, fat, and skin. Adult stem cells are a highly useful cell population in regenerative medicine as their ease of isolation, multilineage differentiation, and potential for autologous transplantation makes them a favorable candidate for clinical translation.

As Dr. Jeffrey Caruth stated, “While progress with stem cells is in the early stages, cosmetic surgeons will be one of the principal players in this new segment of medicine.”

Micro-Needling With Stem Cells

According to the Aesthetics Journal, recent studies suggest that there is significant statistical improvement in skin hdyration, melanin, texture, dermal thickness and collagen by combining mirconeedling with stem cell treatments, compared to microneedling alone, The marked improvement of this combination has to do with the issue of penetration and absorption. The message molecules attach to a cell receptor and that cell makes more of the same chemical. It then excretes it between cells to signal the cells nearby and so forth, creating a cascade effect with built in amplification. Single growth factors can distort the process of tissue regeneration. Nature doesn’t apply single growth factors to a problem. They come in complex arrays (cocktails) perfectly balanced for coordinated regeneration.

Stem Cell Technology Triple Approach

Stemology skincare’s proprietary technology, StemCore-3™, utilizes a three-pronged approach for optimal anti-aging results. First Stemology products contain secreted components derived from laboratory grown human Mesenchymal Stem Cells (MSC) cultures. MSC’s are very versatile (commonly called the duct tape of the body) and differentiate to create the structural tissues of the body. Second, plant stem cells are added to the formulation. And while plant stem cells cannot provide growth factors or cytokines that communicate with human cells (the “language” is not the same), the do contain specific epigenetic factors, the function of which is to maintain the self-renewal capacity of stem cells. Finally, a cell-to-cell communicator is incorporated which helps to stimulate dermal fibroblast communication with other skin cells through growth factors and cytokines.

To learn more about scientific advancements in aesthetic stem cell technology, listen to the full webinar “The Roll of Stem Cells and Stem Cell Derivatives in Aesthetics,” visit http://www.medresultsnetwork.com/archivedwebinars/.

For more information about Stemology skincare, visit http://www.medresultsnetwork.com/stemology-skincare/.

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Stemology Becomes Official Partner of MedResults Network (MRN) After Successful Test Period

FOR IMMEDIATE RELEASE

LOS ANGELES, CA – MedResults Network (MRN) announces official partnership with Stemology, the world’s first and only anti-aging skincare brand dedicated to providing all-natural, intelligently organic formulations through the emerging science of adult and plan stem cell technologies. The largest national buying group for aesthetic providers is officially launching the Stemology brand on the heels of successful testing and surpassed sales expectations.

“Adding Stemology to our brand portfolio is extremely exciting as our members are always looking for the latest and best technology in the skin industry,” explains MRN CEO Jeff Routledge. “The brand fuses science and natural, organic formulations, something that’s highly sought-after by professionals in the industry, and consumers alike. Now, MRN Members can have the best of both worlds by offering Stemology products at our exclusive Members – only price.”

“We are so pleased with the success of the brand’s trial with MRN,” adds Stemology Chief Marketing Officer Lori Jacobus. “MRN is the ideal partner and channel for Stemology, targeting more than 2,600 aesthetic medical practices and med spas throughout the U.S., and in turn, their patients and clients. This group really understands the need and demand for quality, efficacy, and eco-aware products that can also serve the growing number of skincare enthusiasts looking for natural formulas backed by clinical science. We are building up sales efforts and look forward to partnering with more MRN accounts in the coming months.”

Stemology products, including bestselling Cell Revive Serum Complete, formulated to address all 12 signs of facial aging – including fine lines and wrinkles, skin elasticity, tightness, tone, and more – are now available to MRN partners.

For more information about MRN and Stemology, visit www.medresultsnetwork.com or www.stemologyskincare.com.

ABOUT THE MEDRESULTS NETWORK

MedResults Network is the nation’s largest buying network for aesthetic medical providers and is based on saving its members time and money! Using the buying power of its 2,600 members, MRN has negotiated with over 50+ national vendors to bring aesthetic providers discounts and rebates on the products and services they use daily. MedResults Network is the only national buying group that offers benefits at no cost to members, with no risk, and with the opportunity for members to continue purchasing directly from their preferred manufacturers and distributors.

ABOUT STEMOLOGY

Stemology is dedicated to providing all-natural, intelligently organic skincare formulations through the emerging science of Stem Cells. Stemology is the first and only brand to bring together both human adult stem cell and plant stem cell technologies, along with a stem cell communicator that greatly enhances intercellular communication to maximize the benefit of stem cell “signaling” growth factors. Stemology products are ethically formulated and do not contain any actual stem cells or DNA. Stemology products are free of phthalates, parabens, GMOs and petrochemicals. Stemology is a cruelty-free company.

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Types of Facial Aging

The 12 Types of Facial Aging

Breaking Down How and Where the Face Ages

Written By: Dr. Hal Simeroth, Chief Technical Officer, Stemology Skincare

Did you know that there are 12 types of facial aging?! Yes…we said twelve! Many skincare lines classify “anti-aging” as one, two or maybe three specific aging types. Maybe it’s wrinkles from your genetic makeup? Maybe it’s hyper-pigmentation from environmental exposure? Or maybe it’s dry skin due to hormonal changes? But the reality is that there is four times the amount of different types of facial aging! Don’t let other skincare brands lump your treatment regimen into one “anti-aging” category!

Stemology looks at the 12 different types of facial aging – and how we can make statistically significant improvements in each of those areas – when creating our products. Recently, we embarked on an ambitious independent clinical trial of our Cell Revive Serum Complete, testing it against the 12 types of facial aging that includes:

  1. Firmness
  2. Elasticity
  3. Hydration
  4. Softness
  5. Appearance of Facial Fine Lines and Wrinkles
  6. Appearance of Fine Lines and Wrinkles Around the Eyes
  7. Appearance of Fine Lines and Wrinkles Around the Mouth
  8. Depth of Wrinkles on Forehead
  9. Facial Deep Wrinkles, including glabellar wrinkles (between the brows)
  10. Hyperpigmentation
  11. Tone/Radiance/Skin Brightness
  12. Pore Size

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Test subjects using the Stemology Cell Revive Serum Complete saw statistically significant improvements in all 12 areas of facial aging over an 8 week period:

  • 62% saw an improvement in the glabellar wrinkles
  • 64% saw an improvement in deep wrinkles
  • 73% saw an improvement in fine lines and wrinkles around the eyes
  • 76% saw improved elasticity
  • 79% saw an improvement in fine lines and wrinkles
  • 79% saw an improvement in fine lines and wrinkles of the forehead
  • 79% saw an improvement in facial age/sun/dark spots
  • 79% experienced increased skin hydration
  • 82% saw an improvement in skin brightness
  • 82% saw an improvement in the appearance of pore size
  • 90% saw an improvement in skin firmness
  • 100% saw an improvement in skin softness

How is this possible? Well, Stemology is the first and only brand with StemCore-3, the powerful technology that brings together human and plant stem cell technologies, along with a communicating agent to help drive ingredients deeper where they can do the most good. This results in helping prevent and improve the number one cause of skin aging: the declining production of epidermal, collagen and elastin cells, which results in skin that is dull, thin and wrinkled, lacking both firmness and elasticity. What’s even better is that Stemology products are intelligently organic, natural and do not contain chemical ingredients derived from petroleum, ethoxylates, formaldehyde donors, sulfates, parabens, GMO’s or artificial colors!

Have you tried Stemology yet?

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Stemology is a new preferred partner of MedResults Network and Guest Blogger.  Members receive discounts and rebates on their unique stem cell-based product line.

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Hero or Hype?

Exploring Stem Cell Technology in Skincare

There has been a lot of talk in the last few years about stem cells in skincare. So, is it just a lot of hype or is stem cell skincare the next hero in the search for ageless beauty? Let’s investigate.

What Are Stem Cells?

Stem cells are single cells that can replicate themselves and differentiate into many cell types. There are many different types and are found in humans, animals and plants.

Of the various types of human stem cells, perhaps the most well-known, and most controversial, are embryonic stem cells (sometimes called pluripotent stem cells). These are the very first cells at the early stage of the embryo that are able to selectively produce all of the different tissues of the human body. Using embryonic stem cells such as these for skincare is neither recommended nor necessary. After birth, the repairing stem cells of the body (often called Mesenchymal stem cells or MSC’s) continue the work on conducting the repair and rejuvenation of the various structural parts of body tissues (bone, ligaments, muscles, skin, nerve, eye, etc.). They continue this tissue specific work throughout our lives, but, because they differentiate over time into other types of cells, our number of MSC’s decreases as we age. A third type of stem cell, more differentiated and more tissue specific, are often referred to as progenitor cells. They are in the “center” between stem cells and fully differentiated cells.

Like human stem cells, plant stem cells have the ability to self-renew and replace specific plant cells in need of repair. For example, if you break off a plant stem, it grows back within a few weeks thanks to stem cells. That said, unlike human stem cells, the growth factors, cytokines and other proteins, which are the products of plant stem cells, do not have the ability to act in the same way in humans, as in plants. Plant stem cells communicate in a different biochemical “language” that human cells do not recognize. However, plant stem cells do contribute skin-improving nutrients that attribute to overall skin health

Ethical Concerns

One of the biggest concerns people have about stem cells skincare is the ethics involved. As the Chief Technical Officer of Stemology, I have a PhD in bio-ethics. So, ethics are critically important to me personally. There are no actual stem cells or DNA matter in any skincare product claiming stem cell technology. It is in fact the derivatives of the stem cells – the signaling proteins – that are in the formulations. However, how those derivatives are harvested can vary widely by skincare brand. Make sure to do your research when using stem cell skincare and find out where they are getting their stem cell derivatives. And note that Stemology skincare is the first and only skincare line to use both plant stem cells and adult human MSC stem cells, along with a stem cell communicator, to ethically increase the efficacy and effectiveness of our products.

Does It Work?

Yes! There are a number of research papers from doctors and scientists supporting the concept of MSC protein derivatives aiding in skin repair and rejuvenation. And a body of scientific knowledge is rapidly developing which shows the interaction of these growth factors, cytokines, helper proteins, etc in the repair and rejuvenation process for skin. In other parts of the world treatments are actually being done to repair damaged tissue using MSC’s. In fact, the very well respected Journal of Craniofacial Surgery stated “The application of topical growth factors (from MSC) stimulate the repair of facial photo-aging, resulting in new collagen synthesis, epidermal thickening and the clinical appearance of smoother skin with less visible wrinkles.”

Many are saying that stem cell science will completely change medical care, and the skincare industry, as we know it. It’s an exciting time as we are in the infancy stages which means we can look forward to many more advances to come to help as stay naturally younger looking.

To hear the complete presentation of Stem Cells In Skincare: Hero or Hype?, CLICK HERE.

Written By: Dr. Hal Simeroth

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Stemology is a new preferred partner of MedResults Network and Guest Blogger.  Members receive discounts and rebates on their unique stem cell-based product line.

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The Skincare Revolution Is Now

Stemology 101

Introducing Stemology Skincare, the world’s first and only all natural, intelligently organic skincare line backed by clinically proven stem cell science. Bringing together both human and plant stem cell technologies – incorporating the superior features of each – along with a stem cell communicator that greatly enhances intercellular communication to maximize the benefit of stem cell “signaling” growth factors, Stemology has a “best of” approach that maximizes any singular anti-aging approach. Stemology products help prevent and improve the number one cause of skin aging – the declining production of epidermal, collagen and elastin cells, which results in skin that is dull, thin and wrinkled, lacking both firmness and elasticity.

StemCore-3™ Technology

The foundational ingredients of Stemology’s flagship products are based upon 20 years of stem cell research and studying the effects of topical application. StemCore-3 is a proprietary stem cell based peptide complex found only in Stemology products. This methodology produces a unique derivative of stem cell tissue that can be absorbed into the skin. Stem cells, in general, rejuvenate. They trigger the production of new healthy cells in the human body based upon the particular organ cells the stem cell is “encoded” to stimulate. Stem cells are our “natural” defense against deterioration of the body. Since stem cells repair deterioration, the lack of available stem cells contributes to the aging of our organs … including the skin, the largest organ of the human body.

Ethics Policy

Ethics are at the center of the Stemology brand. We will maintain our commitment to use only adult human stem cell technology in our research and in the development of our products. We will not use embryonic stem cells in any of our research work, nor will we use them in the production of our stem cell extracts. None of our products will be made from human fetal tissue; nor will any of our research and development be done with any human fetal tissue. We do not use ingredients from animal products or by-products except for those produced by live animals such as milk, honey, lanolin, etc.  We do not use products that were developed using animal testing, nor do we do any animal testing with our products.

Natural and Intelligently Organic

Stemology products are all natural and intelligently organic. We are dedicated, to the natural origin, purity and safety of the ingredients in our products. We are committed to the use of natural ingredients. The term “natural product” as used in the world of skin care often has a wide variation of meanings. Our definition of a natural product is one that has ingredients derived from chemical compounds found in nature, either in a botanical (herb, flower, root, etc), or the human body (Hyaluronic acid, Coenzyme Q10, protein peptides, etc.).

Stemology products are “intelligently organic.” For a product to be labeled organic each ingredient should be certified “organic.”  Although we have a number of certified organic ingredients in our products, not all of our ingredients are so. We are not striving to have certified organic products and will not label them as such unless they truly are.

What will not be found in our natural skin care products are chemical ingredients derived from petroleum, ethoxylates, formaldehyde donors, sulfates, parabens, GMO’s or artificial colors. This is our commitment our customer and the planet.

Stemology Products

Stemology offers a full range of skincare products for all skincare types including, cleansers, toner, facial serums, eye serum, moisturizers, scrub and masks available for retail, and in the back bar for the discriminating aesthetics professional. To find out more, or place your order, contact Jamie@medresultsnetwork.com.

Author: Lori Jacobus

Stemology is a new preferred partner of MedResults Network and Guest Blogger.  Members receive discounts and rebates on their unique stem cell-based product line.

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stem cells

Do Skin Care Products Containing Stem Cells Actually Make You Look Younger?

Women’s Health Magazine Asks, Dr. Hal Simeroth of Stemology Answers

Excerpted from Women’s Health, December 9, 2015.

As skin-care brands continue to make crazy-scientific advancements, stem-cell products are popping up more and more in dermatology offices and on makeup counters everywhere. So what’s all the hype about?

Your skin is already packed with stem cells. As you age, you start to lose them, and by the time you hit 50, you’ve lost about 98 percent of them. Yikes! “When you’re young, the average turnover for your skin is about 25 to 30 days,” says Hal Simeroth, Ph.D., chief technical officer and founder of Stemology, a stem cell-based skin-care line. “When we get older, the production slows down, [and] the turnover can take up to 60 days. When it’s exposed to the elements longer, it loses that youthful vibrant look.” That’s where products come in.

Stem cells are not without their controversy, though. The use of embryonic ones for research purposes is a hot-button issue (according to the National Institutes of Health, they’re generally derived from embryos that develop from eggs that have been fertilized through IVF and then donated to research).

While some skin-care companies do use human stem cells, they come from adults, not emrbyos—and most products on the market contain plant-based stem cells. Simeroth explains that the stem-cell skin-care products you see on the shelf don’t even contain actual stem cells, but rather the proteins and amino acids that the youthful cells secrete.

“This is what your body recognizes and can use to help rejuvenate and repair cells,” says Simeroth. “These are the natural body healers.”

The cocktail of proteins and amino acids that are harvested from the actual stem cells themselves signal your own cells to produce more collagen and elastin and ultimately fire up the rejuvenation process. Say hello to the fountain of youth!

It’s important to note that stem-cell science is still in its infancy, and even though not all dermatologists are totally convinced that stem cells by themselves are miracle anti-agers, they do agree that these products are still packed with age-defying benefits.

The key to harnessing these age-defying effects is to start young. “We’re trying to mimic what the body does naturally when you’re younger by resorting the growth factor,” says Simeroth. In other words: Start the stem-cell regimen sooner, and you’ll slow down your natural aging process.

Author:  Jennifer Newton

Want to find out more about stem cell skincare products? Contact Jamie@medresultsnetwork.com about Stemology, the world’s first and only skincare line to combine adult stem cell derivatives with plant stem cell nutrients and ingredient “helpers” to create all natural, intelligently organic, highly efficacious anti-aging skincare products that are clinically proven to work.

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